Rifamycin derivatives are antibiotics that work by binding to and inhibiting the mycobacterial DNA dependent RNA polymerase. These antibiotics are bacteriocidal and therefore extremely effective antituberculosis agents, but resistance can develop rapidly if used as a single agent. They easily penetrate into cells, body fluids and cerebrospinal fluid so can be used against organisms in …

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You can spread TB to others even if you do not yet have symptoms. TB mostly affects the lungs, but almost any part of the body can be infected. You may have any of the following: A fever or night sweats Weight loss without trying Tiredness A cough for at least 3 weeks Blood in …

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Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. TB is a severe infection caused by bacteria called Mycobacterium tuberculosis. TB usually starts in the lungs. The bacteria are easily spread from one person to another through the air. They can live in your body a long time …

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